Table 3. Binary logistic regression analysis showing which features of Crohn’s disease activity assessed in magnetic resonance enterography at week 0 were associated with a secondary non-response in patients treated with anti-TNF antibodies. Data are presented as odds ratios (OR) with 95% confidence intervals (CI).

Feature	Statistical significance in predicting secondary non-response to anti-TNF therapy	The percentage overall correct classifications
Bowel wall thickening	1 point: OR 0.6; 95% CI (0.2 – 1.7); ns	—
	2 points: OR 0.1; 95% CI (0.001 – 10); ns
Contrast enhancement	1 point: OR 1.1; 95% CI (0.4 – 25); ns	—
	2 points: OR 1.1; 95% CI (0.04 – 33.3); ns
Fat wrapping	OR 0.9; 95% CI (0.3 – 2.5); ns	—
Proliferation of mesenteric vasculature	1 point: OR 1.2; 95% CI (0.6 – 2.5); ns	—
	2 points: OR 1.6; 95% CI (0.1 – 25); ns
Lymphadenopathy	1 point: OR 1.1; 95% CI (0.5 – 2); ns	—
	2 points: OR 1.2; 95% CI (0.07 – 20); ns
Bowel wall ulcerations	Analysis impossible due to too few cases of ulcerations (4 cases, all in the long-term responders group) in analyzed sample	—
Stenosis	1 point: OR 2.4; 95% CI (1.2 - 5); p = 0.01	75.40%
	2 points: OR 5.8; 95% CI (1.4 – 25); p = 0.01
Intra-abdominal fistulas	OR 1.4; 95% CI (1.1 – 2); p = 0.004	75,5%
Disease extent	1 point: OR 0.6; 95% CI (0.3 – 1.25); ns	—
	2 points: OR 0.4; 95% CI (0.08 – 1.6); ns