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Whole-cell patch-clamp recording of CA3 pyramidal cells during KA-Os. Example traces of spontaneous activity recorded from CA3 pyramidal cells in voltage clamp mode at holding potential 0 mV (blue) and −50 mV (red) in hippocampal slices prepared from P5 (A) and P15 (B) rats in the presence of 300 nM—kainate. Below are shown simultaneous LFP recordings (black) from CA3 pyramidal cell layer in vicinity of the patched cell.
