Table 1.
Baseline characteristics of the sample according to renal function category defined by eGFR (standard deviations in brackets unless otherwise stated as % for categorical variables)
| Total |
eGFR, <45 |
eGFR, 45–59 |
eGFR, ≥60 |
P | |
|---|---|---|---|---|---|
| n = 622 | n = 65 (10.5%) | n = 144 (23.2%) | n = 413 (66.4%) | ||
| eGFR mean | 68.4 (18.9) | 36.4 (7.2) | 53.3 (3.7) | 78.7 (13.4) | .000 |
| Demographics | |||||
| Age | 79.7 (5.5) | 82.0 (6.2) | 80.0 (5.4) | 79.2 (5.4) | .001 |
| Females (%) | 377 (60.6) | 37 (56.9) | 101 (70.1) | 239 (57.9) | .028 |
| Caucasian | 429 (69.0) | 43 (66.2) | 92 (63.9) | 294 (71.2) | .232 |
| Education, yrs | 14.1 (3.5) | 13.0 (3.4) | 14.3 (3.4) | 14.2 (3.5) | .022 |
| Vascular variables | |||||
| Anemia (%) | 85 (13.7) | 9 (13.8) | 27 (18.8) | 49 (11.9) | .117 |
| CVD morbidity (%) | 448 (72.0) | 63 (96.9) | 119 (82.6) | 266 (64.4) | .000 |
| Past smokers (%) | 331 (53.5) | 41 (63.1) | 74 (51.4) | 216 (52.7) | .517 |
| Smokers (%) | 27 (8.2) | 3 (7.5) | 7 (9.6) | 17 (7.8) | .878 |
| BMI | 27.3 (4.8) | 26.8 (4.6) | 28.0 (5.2) | 27.2 (4.7) | .128 |
| Mood | |||||
| GDS | 2.12 (2.04) | 2.7 (2.3) | 2.2 (2.2) | 2.0 (2.0) | .023 |
| Genes | |||||
| APOE ε4 (%) | 127 (23.6) | 17 (13.4) | 26 (20.5) | 84 (23.4) | .399 |
Abbreviations: eGFR, estimated glomerular filtration rate; CVD morbidity, cerebrovascular disease morbidity; BMI, body mass index; GDS, Geriatric Depression Scale; APOE ε4, apolipoprotein E allele e4.
NOTE. Individuals with dementia have been excluded.
NOTE. All percentages are column percentages. This includes history of myocardial infarction, history of stroke, diagnosis of diabetes, and hypertension. The Pearson's chi-square was used for categorical variables.