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. 2015 Mar 27;12(1):945–952. doi: 10.3892/mmr.2015.3557

Table V.

Gene Ontology terms significantly downregulated by microRNAs.

Gene Ontology term P−value Fold enrichment
Phosphate metabolic process 7.05×10−4 2.78
Phosphorus metabolic process 7.05×10−7 2.78
Enzyme linked receptor protein signaling pathway 2.62×10−3 4.22
Protein amino acid phosphorylation 3.29×10−3 2.97
Regulation of cell development 5.26×10−3 5.28
Response to endogenous stimulus 6.57×10−3 3.56
Regulation of epithelial cell proliferation 6.88×10−3 10.16
Cell fate commitment 7.05×10−3 6.49
Transmembrane receptor protein tyrosine kinase signaling pathway 7.60×10−3 4.83
Cell morphogenesis involved in differentiation 1.08×10−2 4.44
Cell projection morphogenesis 1.09×10−2 4.42
Phosphorylation 1.14×10−2 2.48
Cell part morphogenesis 1.30×10−2 4.23
Cell morphogenesis 1.31×10−2 3.55
Response to hormone stimulus 1.51×10−2 3.44
Cell projection organization 1.53×10−2 3.43
Response to organic substance 1.64×10−2 2.50
Cellular component morphogenesis 2.13×10−2 3.18
Peptidyl−tyrosine phosphorylation 2.62×10−2 11.76
Regulation of system process 2.70×10−2 3.50
Peptidyl−tyrosine modification 2.83×10−2 11.27
Positive regulation of programmed cell death 3.09×10−2 2.92
Positive regulation of cell death 3.15×10−2 2.90
Cell adhesion 3.69×10−2 2.32
Biological adhesion 3.71×10−2 2.32
Regulation of synaptic transmission 3.84×10−2 5.31
Negative regulation of transcription, DNA−dependent 4.52×10−2 3.04
Cell−cell signaling 4.53×10−2 2.40
Regulation of transmission of nerve impulse 4.66×10−2 4.91
Negative regulation of RNA metabolic process 4.80×10−2 2.99