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Analysis of SH-SY5Y cell proliferation inhibition rate following EV71 infection, by MTT assay.
| Time (h) | EV71 (MOI=1; %) | PBS (%) | WT (%) |
|---|---|---|---|
| 0 | 1.67±1.68 | 2.32±0.60 | 1.15±1.54 |
| 12 | 29.57±5.75** | 3.90±1.54 | 5.65±2.64 |
| 24 | 47.36±2.52** | 3.88±2.73 | 1.32±1.26 |
| 48 | 48.91±12.54** | 5.22±2.90 | 7.27±2.98 |
| 72 | 61.68±12.19** | 5.37±2.69 | 3.97±0.96 |
P<0.05, vs. WT group; n=3. EV71, enterovirus 71; PBS, phosphate-buffered saline; WT, wild-type; MOI, multiplicity of infection.
