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Effect of SST on LPS-induced microglial activation in the substantia nigra. Brains were immunostained with OX-42 antibody for ana-lyzing the expression of OX-42. (A) Control treated with phosphate-buffered saline, (B) LPS model, (C) LPS + saline, (D) LPS + 20 μg/kg SST, (E) LPS + 40 μg/kg SST, (F) 40 μg/kg SST. Scale bars, 50 μm. LPS, lipopolysaccharide; SST, somatostatin.
