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. 2015 Mar 24;12(1):1075–1081. doi: 10.3892/mmr.2015.3543

Figure 5.

Figure 5

SWH for in situ detection of active NF-κB. (A) Positive signals for activated NF-κB were predominantly detected in the nuclei of the retinal ganglion cells and inner nuclear cells in the vehicle-treated db/db mice. (magnification, ×200). db/db, diabetic db/db mice; LJE-100, db/db mice treated with LJE (100 mg/kg); LJE-250, db/db mice treated with LJE (250 mg/kg). (B) Quantitative analysis of SWH-positive signal intensity. Data are expressed as the mean ± standard error of the mean, n=8. *P<0.01, vs. NOR mice, #P<0.01, vs. vehicle-treated db/db mice. SWH. southwestern histochemistry; NF-κB, nuclear factor-κB; GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer; NOR. normal; LJE, Litsea japonica extract.