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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Biomaterials. 2014 Mar 24;35(18):5006–5015. doi: 10.1016/j.biomaterials.2014.03.005

Fig. 6.

Fig. 6

Intracellular kinetics of P1–13700/YOYO-1-DNA polyplexes (weight ratio of 50) in HeLa cells. (A) Uptake level of polyplexes following incubation at 37 °C for different time (n = 3). (B) Uptake level of polyplexes at 4 °C or in the presence of various en docytic inhibitors. Results were represented as percentage (%) of the uptake level at 37 °C and in the absence of inhibitors (n = 3). (C) CLSM images showing the cellular internalization and distribution of polyplexes in HeLa cells following incubation at 37 °C for 4 h. Cell nuclei were stained with DAPI and the endosomes/lysosomes were stained with Lysotracker Red. Bar represented 10 µm.