Table 2. Network meta-analysis comparison of the efficacy of the the 7 HER2-targeted treatment regimens for overall response rate (ORR).
T-DM1 | 0.59 (0.40,0.85) * | 0.66 (0.42,1.02) | 0.27 (0.17,0.43) * | 0.45 (0.18,0.91) * | 1.23 (0.66,2.11) | 1.03 (0.53,1.76) |
LC | 1.12 (0.97,1.42) | 0.45 (0.36,0.58) * | 0.75 (0.35,1.38) | 2.06 (1.29,3.16) * | 1.72 (0.99,2.81) | |
HC | 0.41 (0.33,0.52) * | 0.67 (0.33,1.23) | 1.85 (1.23,2.66) * | 1.54 (0.89,2.42) | ||
NST | 1.64 (0.77,3.01) | 4.53 (2.79,6.94) * | 3.80 (1.13,6.40) * | |||
ORR | PEC | 3.04 (1.48,5.60) * | 2.59 (1.25, 5.26) * | |||
PEHC | 0.86 (0.45, 1.55) | |||||
LHC |
* The difference between A and B has statistical significance with its confidence interval without 1