Figure 5.

Intraocular pressure elevation in primate eyes with experimental glaucoma. (A) Intraocular pressure measurements from the control eye (white circles) and contralateral eye of a monkey that underwent photocoagulation of the trabecular meshwork (black triangles) before and after treatment on week 0 (black line). Timolol was given on weeks 17 and 18 to the treated eye to reduce the pressure. (B) The mean IOP from the experimental treated eye (Exp) of monkeys used in this study was significantly higher than in the untreated contralateral control eye (Cont; P = 0.006, n = 6). (C) Cup-disc ratios of experimental and contralateral control eyes (P = 0.043, n = 6). (D) The intensity of RGC marker Brn-3b in immunoblots from experimental eyes was reduced as compared with the contralateral control eye (P = 0.002, n = 6).