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. 2015 May 20;10(5):e0126719. doi: 10.1371/journal.pone.0126719

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© 2015 Behrouzvaziri et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 7 — A: The mechanism of HD sensitization by the orexin receptor antagonist. SB suppresses activation of the inhibitory population Inh_HD by orexinergic input which disinhibits HD and thus lowers its activation threshold. B: Effect of SB on the basal inhibitory tone to HD population γ _HD when it is used as an SB-affected parameter instead of w _HD. *—the estimate is statistically significantly different from the one for Vehicle (SB-0, p<0.05); #—the estimates are statistically significantly different between SB 10 and SB 30 (p<0.05). See Results for more details.