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. Author manuscript; available in PMC: 2016 Jun 30.
Published in final edited form as: Psychiatry Res. 2015 Apr 3;232(3):219–225. doi: 10.1016/j.pscychresns.2015.03.007

Fig. 4.

Fig. 4

Increased hippocampal blood volume, but not flow, in schizophrenia

Hemodynamic parameters (mean ± SD) for healthy controls and patients with schizophrenia generated from dynamic susceptibility contrast-(DSC)-MRI for the hippocampus. These values are averaged across hemisphere and slice along the long axis of the hippocampus. Fig. 4A illustrates increased hippocampal cerebral blood volume (CBV) in schizophrenia (one-tailed t-test, t(28) = 1.831, p = 0.039). Fig. 4B illustrates no group differences in hippocampal cerebral blood flow (CBF, one-tailed t-test, t(28) = −0.629, p = 0.28), and Fig. 4C illustrates no difference in hippocampal mean transit time (MTT) in schizophrenia (two-tailed t-test, t(28) = −1.230, p = 0.22). *p < 0.05.