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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Stem Cell Res. 2015 Mar 25;14(3):347–355. doi: 10.1016/j.scr.2015.03.002

Figure 1. Known reproductive toxicants decrease total germ cell viability in hESCs differentiated into spermatogenic cells.

Figure 1

Graphical representation showing that increasing concentrations of 2-BP and DBCP induce germ cell death in hESCs differentiated in in vitro spermatogenic conditions. Acute treatment with each reproductive toxicant was for 24 hours. Data shown represent average values +/ standard deviation from 3 separate experiments. * represents p < 0.01 statistical significance for 2-BP, # represents p < 0.01 for DBCP. % Viability was determined by normalizing values for 2-BP and DBCP to control values from modified MTT Assays.