Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Magn Reson Imaging. 2015 Apr 10;41(6):1487–1504. doi: 10.1002/jmri.24767

Figure 7.

Figure 7

Example of diffusion parameters of samples with different degrees of cartilage damage. A. Histology with safranin-O and diffusion maps (MD and FA) of samples with different grades of cartilage damage as shown by the OARSI scores. Maps show a clear trend of increased MD with increasing OARSI score and a less pronounced decrease in the FA. B. Box plot of the averaged MD over the 50% most superficial cartilage and averaged FA over the whole cartilage depth. Blue indicates average over intact cartilage (n=14 OARSI 0) and red average over cartilage with sign of degradation (OARSI 1 n = 11; OARSI 2 n = 12; OARSI ≥ 3 n = 6). Stars represent statistical significance with respect to the OARSI 0 group. Circles indicate outliers.