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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Headache. 2015 Apr 22;55(5):646–657. doi: 10.1111/head.12571

Table 3. Odds ratios (OR) and 95% confidence intervals (CI) of migraine status according to quartiles of serum lipids and lipoproteins.

No Migraine
(N = 866)
n (%)
Yes Migraine
(N = 196)
n (%)
Unadjusted OR
(95%CI)
Adjusted OR
(95%CI)
Total cholesterol (mg/dL)
Q1 (<219) 210 (24.3) 37 (18.9) 1.00 (REF) 1.00 (REF)
Q2 (219-247) 216 (24.9) 40 (20.4) 1.05 (0.65-1.71) 1.05 (0.64-1.70)
Q3 (248-281) 220 (25.4) 46 (23.5) 1.19 (0.74-1.90) 1.16 (0.72-1.86)
Q4 (≥282) 220 (25.4) 73 (37.2) 1.88 (1.21-2.92) 1.87 (1.20-2.91)
P value for trend 0.002 0.003
HDL cholesterol (mg/dL)
Q1 (<56) 209 (24.1) 45 (23.0) 0.84 (0.54-1.29) 0.80 (0.52-1.24)
Q2 (56-63) 203 (23.4) 51 (26.0) 0.98 (0.64-1.49) 0.95 (0.62-1.45)
Q3 (64-72) 228 (26.3) 42 (21.4) 0.72 (0.46-1.11) 0.70 (0.45-1.08)
Q4 (≥73) 226 (26.1) 58 (29.6) 1.00 (REF) 1.00 (REF)
P value for trend 0.713 0.560
LDL cholesterol (mg/dL)
Q1 (<117) 208 (24.0) 35 (17.9) 1.00 (REF) 1.00 (REF)
Q2 (117-140) 219 (25.3) 47 (24.0) 1.28 (0.79-2.05) 1.25 (0.77-2.02)
Q3 (141-169) 221 (25.5) 50 (25.5) 1.34 (0.84-2.15) 1.30 (0.81-2.09)
Q4 (≥170) 218 (25.2) 64 (32.6) 1.74 (1.11-2.75) 1.70 (1.08-2.69)
P value for trend 0.017 0.023
Triglyceride (mg/dL)
Q1 (<170) 212 (24.5) 46 (23.5) 1.00 (REF) 1.00 (REF)
Q2 (170-206) 218 (25.2) 43 (21.9) 0.91 (0.58-1.44) 0.88 (0.56-1.40)
Q3 (207-252) 218 (25.2) 38 (19.4) 0.80 (0.50-1.28) 0.79 (0.49-1.26)
Q4 (≥253) 218 (25.2) 69 (35.2) 1.46 (0.96-2.22) 1.39 (0.91-2.14)
P value for trend 0.087 0.133
Total cholesterol:HDL ratio
Q1 (<3.4) 214 (24.7) 32 (16.3) 1.00 (REF) 1.00 (REF)
Q2 (3.4-3.8) 204 (23.6) 50 (25.5) 1.64 (1.01-2.66) 1.65 (1.01-2.68)
Q3 (3.9-4.4) 229 (26.4) 55 (28.1) 1.61 (0.99-2.58) 1.50 (0.93-2.41)
Q4 (≥4.5) 219 (25.3) 59 (30.1) 1.80 (1.13-2.88) 1.73 (1.07-2.78)
P value for trend 0.026 0.054

Adjusted for maternal age, parity and pre-pregnancy BMI.

Separate models were fitted for each lipid or lipoprotein