Table 3. Odds ratios (OR) and 95% confidence intervals (CI) of migraine status according to quartiles of serum lipids and lipoproteins.
No Migraine (N = 866) n (%) |
Yes Migraine (N = 196) n (%) |
Unadjusted OR (95%CI) |
Adjusted OR (95%CI) |
|
---|---|---|---|---|
Total cholesterol (mg/dL) | ||||
Q1 (<219) | 210 (24.3) | 37 (18.9) | 1.00 (REF) | 1.00 (REF) |
Q2 (219-247) | 216 (24.9) | 40 (20.4) | 1.05 (0.65-1.71) | 1.05 (0.64-1.70) |
Q3 (248-281) | 220 (25.4) | 46 (23.5) | 1.19 (0.74-1.90) | 1.16 (0.72-1.86) |
Q4 (≥282) | 220 (25.4) | 73 (37.2) | 1.88 (1.21-2.92) | 1.87 (1.20-2.91) |
P value for trend | 0.002 | 0.003 | ||
HDL cholesterol (mg/dL) | ||||
Q1 (<56) | 209 (24.1) | 45 (23.0) | 0.84 (0.54-1.29) | 0.80 (0.52-1.24) |
Q2 (56-63) | 203 (23.4) | 51 (26.0) | 0.98 (0.64-1.49) | 0.95 (0.62-1.45) |
Q3 (64-72) | 228 (26.3) | 42 (21.4) | 0.72 (0.46-1.11) | 0.70 (0.45-1.08) |
Q4 (≥73) | 226 (26.1) | 58 (29.6) | 1.00 (REF) | 1.00 (REF) |
P value for trend | 0.713 | 0.560 | ||
LDL cholesterol (mg/dL) | ||||
Q1 (<117) | 208 (24.0) | 35 (17.9) | 1.00 (REF) | 1.00 (REF) |
Q2 (117-140) | 219 (25.3) | 47 (24.0) | 1.28 (0.79-2.05) | 1.25 (0.77-2.02) |
Q3 (141-169) | 221 (25.5) | 50 (25.5) | 1.34 (0.84-2.15) | 1.30 (0.81-2.09) |
Q4 (≥170) | 218 (25.2) | 64 (32.6) | 1.74 (1.11-2.75) | 1.70 (1.08-2.69) |
P value for trend | 0.017 | 0.023 | ||
Triglyceride (mg/dL) | ||||
Q1 (<170) | 212 (24.5) | 46 (23.5) | 1.00 (REF) | 1.00 (REF) |
Q2 (170-206) | 218 (25.2) | 43 (21.9) | 0.91 (0.58-1.44) | 0.88 (0.56-1.40) |
Q3 (207-252) | 218 (25.2) | 38 (19.4) | 0.80 (0.50-1.28) | 0.79 (0.49-1.26) |
Q4 (≥253) | 218 (25.2) | 69 (35.2) | 1.46 (0.96-2.22) | 1.39 (0.91-2.14) |
P value for trend | 0.087 | 0.133 | ||
Total cholesterol:HDL ratio | ||||
Q1 (<3.4) | 214 (24.7) | 32 (16.3) | 1.00 (REF) | 1.00 (REF) |
Q2 (3.4-3.8) | 204 (23.6) | 50 (25.5) | 1.64 (1.01-2.66) | 1.65 (1.01-2.68) |
Q3 (3.9-4.4) | 229 (26.4) | 55 (28.1) | 1.61 (0.99-2.58) | 1.50 (0.93-2.41) |
Q4 (≥4.5) | 219 (25.3) | 59 (30.1) | 1.80 (1.13-2.88) | 1.73 (1.07-2.78) |
P value for trend | 0.026 | 0.054 |
Adjusted for maternal age, parity and pre-pregnancy BMI.
Separate models were fitted for each lipid or lipoprotein