Table 2.
Anthropometric, gross femur geometry, and DXA data of female and male, WT and CD166-/- mice at 6 weeks of age. Results are presented as the mean±SE. *Indicates significant interaction between genotype and sex, with post-hoc analyses indicating sex-specific genotype differences (p<0.05). #Indicates significant main effect for genotype, with no significant interaction found between genotype and sex (p<0.05).
| Strain | Sex | N | Weight (g) | Femur Length (mm) | Femur Width (mm) | Femur Height (mm) | Total Femur aBMD (g/cm2) | Vertebrae aBMD (g/cm2) | Whole Body aBMD (g/cm2) | Total Femur BMC (g) | Vertebrae BMC (g) | Whole Body BMC (g) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | F | 9 | 14.7±0.2 | 12.1±0.2 | 1.63±0.07 | 1.21±0.02 | 0.047±0.001 | 0.039±0.001 | 0.0369±0.0001 | 0.014±0.001 | 0.036±0.001 | 0.22±0.01 |
| CD166-/- | F | 8 | 17.1±0.4# | 12.5±0.2* | 1.65±0.03 | 1.16±0.01 | 0.052±0.003* | 0.044±0.002# | 0.0418±0.0001# | 0.017±0.001* | 0.045±0.002* | 0.31±0.01* |
| WT | M | 10 | 18.3±0.2 | 12.0±0.2 | 1.61±0.05 | 1.26±0.04 | 0.050±0.002 | 0.041±0.001 | 0.0387±0.0006 | 0.016±0.001 | 0.039±0.001 | 0.25±0.01 |
| CD166-/- | M | 7 | 20.7±0.4# | 12.8±0.6* | 1.79±0.04 | 1.27±0.01 | 0.064±0.001* | 0.049±0.001# | 0.0464±0.0001# | 0.021±0.001* | 0.052±0.001* | 0.39±0.01* |