Table 1.
Simulation and Patient Experimental Resultsa
| SNR | Conventional
|
Optimized
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dt (μm2/ms) | SD | fp (%) | SD | Dp (μm2/ms) | SD | Dt (μm2/ms) | SD | fp (%) | SD | Dp (μm2/ms) | SD | ||
| Free | 10 | 1.106 | 0.569 | 21.41 | 17.31 | 15.132 | 11.102 | 1.162 | 0.524 | 20.39 | 17.30 | 15.005 | 11.694 |
| 20 | 1.187 | 0.482 | 17.84 | 14.65 | 16.203 | 11.150 | 1.227 | 0.441 | 16.93 | 13.17 | 15.900 | 11.207 | |
| 39.2 | 1.239 | 0.415 | 15.34 | 10.84 | 16.463 | 10.406 | 1.278 | 0.404 | 13.62 | 8.64 | 16.530 | 10.040 | |
| 80 | 1.296 | 0.387 | 12.27 | 6.30 | 16.957 | 8.716 | 1.314 | 0.391 | 11.43 | 5.30 | 16.949 | 8.315 | |
| Exp. | 1.01 | 0.397 | 28.40† | 15.99 | 8.67 | 4.258 | 1.088 | 0.390 | 24.89* | 11.39 | 11.028 | 7.981 | |
| Segmented | 10 | 1.365 | 0.610 | 7.89 | 16.81 | 17.700 | 8.865 | 1.377 | 0.615 | 6.00 | 20.59 | 15.583 | 8.822 |
| 20 | 1.375 | 0.459 | 8.13 | 8.92 | 19.041 | 8.883 | 1.353 | 0.454 | 8.61 | 10.24 | 16.734 | 8.924 | |
| 39.2 | 1.360 | 0.406 | 8.58 | 5.14 | 19.723 | 8.239 | 1.339 | 0.410 | 9.44 | 5.99 | 17.840 | 8.527 | |
| 80 | 1.362 | 0.394 | 8.61 | 3.55 | 20.569 | 6.546 | 1.339 | 0.391 | 9.56 | 3.80 | 18.159 | 7.267 | |
| Exp. | 1.323 | 0.472 | 13.31*† | 5.05 | 15.31 | 9.634 | 1.195 | 0.471 | 16.83 | 9.06 | 13.183 | 6.529 | |
a
Average values and standard deviation results from the different b-value selection and fitting methods at four levels of SNR and from patient experiments. Daggers represent significant differences between fitting methods free and segmented, while asterisks represent significant (P <0.05) differences between the different b-value selection.