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. 2015 Apr 30;4:200. doi: 10.1186/s40064-015-0990-y

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© Umene et al.; licensee Springer. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Involvement of a pair of direct repeats in the generation of deletions or multiplications. Direct repeats on the region encompassing reiteration VII were indicated by horizontal arrows, and the stretch flanked by a pair of direct repeats was indicated by a double line. (a) Generation of del-2. The misalignment of direct repeats (CCGGGG) during DNA replication indicated by a broken line could result in the generation of the deletion of del-2. (b) Generation of mul-2. The misalignment of direct repeats (TCCC) during DNA replication indicated by a broken line could result in the generation of the multiplication of mul-2 (duplication). Each copy of the duplicated sequences was indicated by a solid line having a closed circle at both ends.