Table 1.

HCMV NK evasion functions

Gene	Target	Conserved
UL18	HLA-1 homologue, binds LIR1	Yes (variable)
UL40	Upregulates HLA-E and gpUL18	Mutation in TB40E, Towne, U8
UL16	MICB, ULBP1, ULBP2	Yes
UL83	Binds NKp30	Yes
miR112	miRNA against MICB	Yes
UL135	Inhibits synapse formation	Deletions in AD169, Towne
UL141	PVR, Nectin 2 TRAIL-R	Deletions in AD169, Towne, TB40E VR1814, some low-passage strains
UL142	MICA	Deletion in AD169, Towne, some low-passage strains
US18	MICA	Yes
US20	MICA	Yes