Table 2.

Functional activity of vIL-10 on lymphoid cells in vitro

Cell type(s)	Phenotype	Ref.
Monocytes	↑ Differentiation into inflammatory macrophages	[26]
	↓ HLA-DR
	↑ CD64, CCR5
PBMC	↓ Mitogen-stimulated proliferation, MHC-I and –II	[27, 28]
	↓ IFN-γ
Monocytes	↓ IL-6, IL-1α, GM-CSF, TNF-α; MHC class I and II
	↑ HLA-G
MDC	↓ TNF-α, IL-6 IL-12, Bcl-2, Bcl-XL	[29, 30]
	↑ cIL-10
PDC	↓ INF-α, IFN-β	[31]