Table 1.
Corrected Mixed Effects Cluster Analysis in Smokers
Cluster | COG x (mm) | COG y (mm) | COG z (mm) | Max Z-statistic | Mean COPE | p |
---|---|---|---|---|---|---|
Anterior Cingulate Cortex/Orbitofrontal Cortex | 1 | 44 | −5 | 3.74 | 44.3 | <.001 |
Superior Frontal Gyrus | −14 | 56 | 28 | 3.28 | 45.8 | .008 |
Occipital Cortex | 14 | −78 | −17 | 3.23 | 42.9 | <.001 |
Group mixed-effects analysis of smoking–neutral contrast demonstrated significant activation in three main clusters consisting of multiple local maxima. COGx, y, z, are the coordinates of the centers of gravity (COG) for each cluster. P represents the P value corresponding to the maximum Z-statistic within each cluster. COPE, contrast of the parameter estimates.