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. 2015 May 24;2015:864739. doi: 10.1155/2015/864739

Table 2.

Change of numerical rating scale scores for anxiety, depression, and stress after therapeutic laughter program.

Intention-to-treat analysis Per-protocol analysis
Experimental
group (n = 31)
Control
group (n = 29)
p value Experimental
group (n = 31)
Control
group (n = 29)
p value
Mean ± SD Mean ± SD Mean ± SD Mean ± SD
Baseline
 Anxiety 3.42 ± 2.08 3.21 ± 2.24 0.66b 3.20 ± 2.31 2.97 ± 1.92 0.70a
 Depression 3.48 ± 2.14 2.97 ± 1.92 0.33a 3.30 ± 2.03 3.21 ± 2.24 0.83b
 Stress 3.32 ± 2.09 3.62 ± 1.95 0.57a 3.35 ± 2.21 3.62 ± 1.95 0.38b
Postintervention
 Anxiety 1.48 ± 1.46 3.31 ± 2.22 <0.01c 1.10 ± 1.41 3.31 ± 2.22 <0.01c
 Depression 1.65 ± 1.62 3.31 ± 2.04 <0.01c 1.30 ± 1.66 3.31 ± 2.04 <0.01c
 Stress 1.26 ± 1.32 3.72 ± 1.81 <0.01c 0.80 ± 1.20 3.72 ± 1.81 <0.01c
Difference
 Anxiety −1.94 ± 1.97 0.10 ± 1.97 <0.01b −2.20 ± 1.85 0.10 ± 1.97 <0.01b
 Depression −1.84 ± 1.63 0.34 ± 1.97 <0.01b −1.90 ± 1.55 0.34 ± 1.97 <0.01b
 Stress −2.06 ± 2.00 0.10 ± 2.14 <0.01b −2.55 ± 1.88 0.10 ± 2.14 <0.01b

p values were calculated by (a) independent t-test, (b) Mann-Whitney test, and (c) analysis of covariance test adjusting for marital status and baseline distress score.