Table 3.
Parameters | Control | 50 mg/kg extract | 500 mg/kg extract | 1000 mg/kg extract | 1.04 mg/kg drug |
---|---|---|---|---|---|
Initial body weight (g) | 348 ± 7.81 | 307 ± 15.82 | 305 ± 28.93 | 309 ± 24.41 | 317 ± 7.81 |
Final body weight (g) | 368 ± 12.42 | 339 ± 14.19 | 342 ± 14.53 | 345 ± 13.47 | 295 ± 12.41 |
Weight gain (%) | 20 | 32∗ | 37∗ | 36∗ | 22 |
Right testis | |||||
Absolute weight (g) | 1.88 ± 0.04 | 1.88 ± 0.11 | 1.95 ± 0.11 | 2.95 ± 0.11∗ | 3.06 ± 0.18∗ |
Weight (g/100 g BW) | 0.63 ± 0.01 | 0.64 ± 0.03 | 0.65 ± 0.04 | 0.75 ± 0.04 | 0.69 ± 0.06 |
Left testis | |||||
Absolute weight (g) | 2.11 ± 0.05 | 2.16 ± 0.02 | 2.51 ± 0.08 | 3.04 ± 0.45∗ | 3.11 ± 0.06∗ |
Weight (g/100 g BW) | 0.67 ± 0.00 | 0.67 ± 0.01 | 0.68 ± 0.02 | 0.62 ± 0.01 | 0.66 ± 0.03 |
Epididymis | |||||
Absolute weight (g) | 0.47 ± 0.05 | 1.42 ± 0.11∗ | 1.46 ± 0.11∗ | 1.48 ± 0.12∗ | 1.49 ± 0.20∗ |
Weight (g/100 g BW) | 0.50 ± 0.03 | 0.44 ± 0.03 | 0.46 ± 0.03 | 0.49 ± 0.04 | 0.51 ± 0.06 |
Seminal vesicle | |||||
Absolute weight (g) | 0.77 ± 0.15 | 0.84 ± 0.12 | 0.93 ± 0.04 | 1.09 ± 0.41 | 0.94 ± 0.10 |
Weight (g/100 g BW) | 0.46 ± 0.03 | 0.24 ± 0.02 | 0.25 ± 0.03 | 0.26 ± 0.11 | 0.26 ± 0.03 |
Prostate gland | |||||
Absolute weight (g) | 1.00 ± 0.10 | 1.07 ± 0.18 | 1.18 ± 0.28 | 1.20 ± 0.22 | 1.19 ± 0.01 |
Weight (g/100 g BW) | 0.60 ± 0.00 | 0.32 ± 0.05 | 0.32 ± 0.07 | 0.35 ± 0.07 | 0.36 ± 0.08 |
Data are expressed as mean ± SD, n = 5. ∗Significant (p < 0.05), ∗∗significant (p < 0.01), ∗∗∗significant (p < 0.001), and ∗∗∗∗highly significant (p < 0.0001) compared with the control group, #significant (p < 0.05) compared with the standard drug.