. 2015 Mar 20;38(6):1138–1144. doi: 10.2337/dc14-2422

Table 1.

Clinical demographic results and neuropathy assessment in control subjects and in DSPN(−) and DSPN(+) patients with type 1 diabetes

Variable	Control subjects  (n = 26)	DSPN(−)  (n = 46)	DSPN(+) (n = 17)
Age, years	44 ± 15	44 ± 13	59 ± 11
Duration of diabetes, years	N/A	23 ± 15	39 ± 14
HbA_1c (%)^‡	5.5 ± 0.3	8.2 ± 1.4	8.5 ± 1.3
HbA_1c (mmol/mol)^‡	37.1 ± 3.5	62.2 ± 24.1^¶	69.3 ± 14.3^¶
BMI (kg/m²)^*	26.8 ± 4.0	26.4 ± 4.5	27.5 ± 3.5^¶
Cholesterol (mmol/L)
Total^*	5.0 ± 0.8	4.4 ± 0.9^¶	4.3 ± 0.9^¶
HDL	1.5 ± 0.3	1.6 ± 0.5	1.6 ± 0.4
Triglycerides (mmol/L)	1.4 ± 0.7	1.2 ± 0.7	1.3 ± 0.6
Blood pressure (mmHg)
Systolic^†	126.7 ± 16.3	130.3 ± 17.8^¶	141.1 ± 25.2^¶^§
Diastolic	70.2 ± 9.1	71.6 ± 9.6	73.0 ± 9.8
VPT (V)^‡	6.0 ± 5.5	7.6 ± 5.5	25.2 ± 13.4^¶^§
WT (°C)^†	36.4 ± 2.0	38.7 ± 3.6^¶	43.5 ± 4.6^¶^§
CT (°C)^†	28.8 ± 1.6	27.1 ± 2.7^¶	16.8 ± 10.6^¶^§
PMNCV (m/s)^‡	49.1 ± 3.4	43.9 ± 3.1^¶	31.0 ± 9.5^¶^§
SSNCV (m/s)^‡	50.9 ± 3.9	45.3 ± 5.2^¶	37.8 ± 6.8^¶^§
PMNamp (μV)^‡	6.0 ± 2.4	6.0 ± 8.3	1.6 ± 1.6^¶^§
SSNamp (μV)^‡	19.7 ± 8.3	12.5 ± 6.9^¶	4.3 ± 3.5^¶^§
IENFD^¿	9.8 ± 3.7	7.0 ± 5.0^¶	5.0 ± 5.5^¶^§
Manual
CNFD^‡	36.8 ± 5.3	28.3 ± 7.2^¶	16.9 ± 10.1^¶^§
CNBD^*	92.8 ± 36.4	56.1 ± 30.3^¶	48.2 ± 32.9^¶
CNFL^‡	26.7 ± 3.7	20.2 ± 5.1^¶	14.8 ± 8.3^¶^§
Automated
CNFD^‡	31.3 ± 6.5	22.6 ± 7.3^¶	13.5 ± 9.1^¶^§
CNBD^‡	44.6 ± 17.2	26.2 ± 15.1^¶	15.4 ± 12.1^¶^§
CNFL^‡	17.7 ± 2.8	13.4 ± 3.3^¶	8.8 ± 4.7^¶^§

Results are expressed as mean ± SD.

N/A, not applicable for this group.

Statistically significant differences using ANOVA/Kruskal-Wallis:

*P < 0.05;

¿P < 0.01;

†P < 0.001;

‡P < 0.0001.

Post hoc results for DSPN(+) significantly different from

¶control subjects and

§DSPN(−).