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DPP-4 inhibition reduces WD-induced hepatic steatosis and hepatic TAG accumulation. Values are means ± SE. A: Hematoxylin and eosin staining of hepatocytes for lipid droplets. B: Hepatic lipids were extracted and analyzed by liquid chromatography–mass spectrometry, and hepatic TAG content was determined as fatty acid content of TAG. C: Distribution of fatty acid species in TAG. n = 5 per group. *P < 0.01, main effect of diet. #P < 0.01, diet-by-drug interaction, WD-MK vs. WD.
