Table 5.
Patients with an MMSE score ≥24: CERAD-NB subtests with maximum scores, mean scores, standard deviations, minimum and maximum scores for FTLD and AD groups and group-wise comparisons of the differences
| CERAD-NB subtest (maximum score) | FTLD, mean±SD (range) | n | AD, mean±SD (range) | n | t value | p (2-tailed) | Cohen's d value |
|---|---|---|---|---|---|---|---|
| Verbal Fluency (animals) | 14.2±5.1 (5–25) | 42 | 15.5±4.6 (7–26) | 40 | 0.2092 | ||
| Boston Naming Test (15) | 10.7±3.8 (1–15) | 42 | 11.6±2.3 (7–15) | 40 | 1.35 (67)1 | 0.183 | −0.297 |
| MMSE (30) | 26.4±1.7 (24–30) | 43 | 25.9±1.6 (24–30) | 40 | −1.36 (81) | 0.179 | 0.303 |
| Word List Learning (30) | 16.6±4.5 (7–27) | 43 | 15.7±4.3 (8–26) | 40 | 0.3132 | ||
| Constructional Praxis (11) | 9.4±1.5 (6–11) | 39 | 9.4±1.8 (5–11) | 39 | 0.07 (76) | 0.947 | −0.018 |
| Word List Delayed Recall (10) | 4.9±1.9 (1–10) | 43 | 3.2±2.1 (0–8) | 39 | −3.83 (80) | ≤0.001 | 0.669 |
| Word List Delayed Recall Savings, % (100) | 71.7±22.7 (17–100) | 43 | 48.8±27.8 (0–100) | 39 | −4.11 (80) | ≤0.001 | 0.903 |
| Word List Recognition (20) | 17.7±2.4 (11–20) | 41 | 17.1±2.1 (12–20) | 40 | −1.26 (79) | 0.212 | 0.279 |
| Word List Discriminability (10) | 7.8±2.4 (1–10) | 40 | 7.1±2.1 (0–10) | 38 | −1.29 (76) | 0.200 | 0.294 |
| Word List Recognition, % (100) | 88.7±12.0 (55–100) | 41 | 85.5±10.5 (60–100) | 40 | −1.26 (79) | 0.212 | 0.280 |
| Total Recall (30) | 22.7±3.8 (12–30) | 41 | 20.2±3.4 (15–28) | 39 | 0.0022 | ||
| Constructional Praxis: Delayed Recall (11) | 7.1±2.6 (0–11) | 39 | 4.8±3.7 (0–11) | 39 | −3.19 (68)1 | 0.002 | 0.725 |
| Constructional Praxis: Savings, % (100) | 74.8±24.7 (0–100) | 39 | 50.6±37.4 (0–100) | 39 | −3.37 (66)1 | 0.001 | 0.764 |
| Clock Drawing (6) | 4.2±1.8 (1–6) | 41 | 4.4±1.9 (0–6) | 40 | 0.38 (79) | 0.708 | −0.086 |
| Memory Total Score (41) | 29.7±4.9 (17–39) | 37 | 25.1±5.8 (16–39) | 38 | 0.0012 | ||
| Memory Index, % (100) | 74.3±16.4 (24–100) | 36 | 57.8±20.1 (20–93) | 37 | 0.0012 | ||
| Total Score (100) | 63.4±12.5 (35–92) | 37 | 62.4±11.2 (41–95) | 38 | 0.4682 |
1
The t test was used for unequal variances, with a Levene's test significance level of ≤0.05.
2
The Mann-Whitney U test was used because values were not normally distributed.