Table 6.

Brain regions showing relative perfusion changes in the 3 treatment groups

	Donepezil		Rivastigmine		Galantamine
	Z-score	region	Z-score	region	Z-score	region
rCBF increase
Left	4.41	Medial frontal gyrus, GM (BA 11)	4.36	Cuneus	4.01	Superior temporal gyrus, GM (BA 13)
	4.22	Precuneus, GM (BA 31)	3.75	Precuneus, WM	3.53	Lateral globus pallidus
	4.15	Middle temporal gyrus, WM	3.35	Middle frontal gyrus, GM (BA 8)	3.37	Precentral gyrus, GM (BA 4)
	3.89	Insula, WM
	3.33	Middle frontal gyrus, GM (BA 9)
	3.20	Middle frontal gyrus, WM
	3.10	Postcentral gyrus, WM
	3.02	Middle frontal gyrus, GM (BA 10)
Right	4.05	Putamen	5.19	Middle occipital gyrus, GM (BA 19)	3.74	Middle occipital gyrus, GM (BA 19)
	3.84	Superior frontal gyrus, WM	3.66	Lingual gyrus, WM	3.37	Lentiform nucleus
	3.20	Superior frontal gyrus, GM (BA 10)	3.39	Precuneus, GM (BA 7)
	3.20	Superior frontal gyrus, WM	3.32	Thalamus (medial dorsal nucleus)
			3.24	Thalamus
rCBF decrease
Left	−3.01	Superior temporal gyrus, WM	−3.00	Cingulate gyrus, GM (BA 24)	−3.08	Sublobar, extranuclear, WM
	−3.05	Cuneus, WM	−3.34	Inferior semilunar lobule, GM	−3.10	Subgyral, WM
	−4.59	Sublobar, extranuclear, WM	−3.64	Middle temporal gyrus, GM (BA 21)	−3.18	Inferior parietal lobule, WM
	−5.43	Sublobar, extranuclear, WM	−3.76	Medial frontal gyrus, GM (BA 10)	−3.26	Caudate head
			−3.98	Subgyral, WM	−3.38	Caudate tail
			−4.02	Cingulate gyrus, GM (BA 31)
			−4.06	Superior temporal gyrus, GM (BA 38)
			−4.45	Subgyral
Right	−3.01	Thalamus (medial dorsal nucleus)	−3.00	Subgyral, WM	−3.18	Middle temporal gyrus, WM
	−3.38	Supramarginal gyrus, WM	−3.50	Inferior temporal gyrus, GM (BA 20)	−3.82	Anterior cingulate
	−3.56	Middle temporal gyrus, GM (BA 21)	−4.00	Temporal lobe	−3.87	Cingulate gyrus, WM
	−3.86	Superior temporal gyrus, WM	−4.31	Anterior cingulate, GM (BA 32)
	−4.02	Medial frontal gyrus, GM (BA 6)	−4.73	Sublobar, extranuclear, WM
	−4.80	Uncus, GM (BA 28)

Regions with Z-score changes ≥3 are shown. GM = Gray matter; WM = white matter; BA = approximate Brodmann area.