Table 3.

Inhibitors of epigenetic readers

Category	Compound	Phase	Tumour type	References
Bromodomain inhibitors
BET inhibitors	JQ1	Preclinical	NUT midline carcinoma, MLL-rearranged leukaemia, multiple myeloma	Filippakopoulos et al., 2010; Dawson et al., 2011; Delmore et al., 2011
	I-BET151	Preclinical	Multiple myeloma	Chaidos et al., 2014
	I-BET762	Clinical trials	Haematological malignancies, NUT midline carcinoma, solid tumours	NCT01943851; NCT01587703
BAZ2B inhibitors	GSK2801	Preclinical	(Enzymic inhibition of the target protein)	http://www.thesgc.org/chemical-probes/GSK2801
Chromodomain inhibitors
L3MBTL1 inhibitors	UNC669	Preclinical	(Enzymic inhibition of the target protein)	Herold et al., 2011
L3MBTL3 inhibitors	UNC1215	Preclinical	(Enzymic inhibition of the target protein)	James et al., 2013