Table 2.
Serum and synovial fluid (SF) concentrations of proinflammatory cytokines in children with juvenile idiopathic arthritis (JIA) and healthy controls (Ctrl)
| Cytokines (pg/ml) | Serum | SF | |||
|---|---|---|---|---|---|
| JIA n = 50 mean ± SD | Ctrl n = 29 mean ± SD | JIA vs. Ctrl p | n = 18 mean ± SD | Serum vs. SF p | |
| TNF-α | 7.0 ±3.2 | 5.8 ±5.9 | > 0.05 | 13.5 ±14.5 | 0.038 |
| IL-1β | 2.6 ±1.7 | 1.9 ±0.5 | 0.011 | 11.6 ±26.0 | 0.013 |
| IL-6 | 62.6 ±98.2 | 11.8 ±4.9 | 0.007 | 2962.2 ±1273.3 | < 0.001 |
| IL-17 | 1.4 ±1.2 | 0.6 ±0.4 | 0.008 | 1.95 ±1.0 | > 0.05 |
| IL-21 | 656.5 ±2157.1 | 152.7 ±126.5 | > 0.05 | 206.08 ±253.9 | > 0.05 |
| IL-23 | 93.5 ±139.6 | 23.5 ±43.2 | 0.023 | 62.74 ±97.1 | > 0.05 |