Figure 3.

Sorcin silencing induced cell cycle arrest and apoptosis in human myeloma cell lines. A. Cells were treated with negative control and shRNA#1 and shRNA#2 for 24 h. PI staining was used to analyze the cell cycle distribution; B. Apoptosis of treated cells assessed by Annexin V-fluorescein isothiocyanate and propidium iodide (PI) double staining and fluorescence-activated cell sorter analysis; The statistical significance was considered as *P<0.05 and **P<0.01 where compared with control.