Table 4.

Correlation analysis of Hes expression and clinical factors of ankylosing spondylitis (AS) patients, including sex, age, course of disease and onset age

Parameters	Cases	-	+	++	+++	Positive rate	P value
Sex
Female	4	0	1	1	2	75%	0.91
Male	18	2	2	3	11	77.8%
Age (year)
< 45	15	1	2	3	9	80%	0.66
≥ 45	7	1	1	1	4	71.4%
Course of disease (year)
< 5	12	0	0	2	10	100%	0.01*
≥ 5	10	2	3	2	3	50%
Onset age (year)
< 20	9	1	1	2	5	77.8%	0.96
≥ 20	13	1	2	2	8	92.3%

Hes, hairy and enhancer of split.