Figure 3.

Resveratrol induced the decrease of SphK activity in K562 cells and changes of S1P and ceramide levels. A. SphK activity in K562 cells was decreased by treatment of resveratrol. B. Quantitative analysis of the secretion of S1P in K562 cells estimated by ELISA assay. C. Quantitative analysis of the secretion of ceramide in K562 cells estimated by ELISA assay. The bars indicated mean ± S.D. (n=3). *P < 0.05, **P < 0.01 vs. vehicle control. Triplicate experiments were performed with triplicate samples.