Table 2.
Frequencies of CAT gene polymorphisms in healthy volunteers and workers with noise exposure
| NCBI rsrs# | Location | Position | Variant | MAF (Hapmap-HCB) | healthy volunteers | workers with noise exposure | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||||
| Genotype, N | MAF | HWE | Genotype, N | MAF | HWE | |||||||||
| rs208679 | 5’flanking | -6411 | A/G | 0.22 | AA 130 | AG 82 | GG 13 | 0.24 | 0.99 | AA 285 | AG 179 | GG 30 | 0.24 | 0.79 |
| rs10836233 | 5’flanking | -2900 | G/A | 0.30 | GG 107 | GA 94 | AA 24 | 0.32 | 0.62 | GG 261 | GA 171 | AA 60 | 0.30 | 0.09 |
| rs2300182 | Intron1 | 7376 | T/A | 0.23 | TT 155 | TA 66 | AA 4 | 0.16 | 0.33 | TT 331 | TA 144 | AA 19 | 0.18 | 0.50 |
| rs769217 | exon9 (synon) | 22436 | T/C | 0.49 | TT 41 | TC 124 | CC 60 | 0.46 | 0.10 | TT 108 | TC 243 | CC 143 | 0.46 | 0.80 |
| rs7104301 | 3’flanking | 33166 | A/G | 0.23 | AA 124 | AG 85 | GG 16 | 0.26 | 0.98 | AA 279 | AG 184 | GG 31 | 0.25 | 0.93 |
| rs7949972 | 3’flanking | 41570 | C/T | 0.45 | CC 76 | CT 110 | TT 39 | 0.42 | 0.78 | CC 169 | CT 222 | TT 103 | 0.43 | 0.06 |
MAF indicates minor allele frequency; HWE indicates Hardy-Weinberg Equilibrium.