Table 3.
Frequencies of CAT gene polymorphisms in all workers without NIHL (-) and with NIHL (+)
| NCBI rs# | Location | Position | Variant | MAF (Hapmap-HCB) | without NIHL (-) | with NIHL (+) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||||
| Genotype, N | MAF | HWE | Genotype, N | MAF | HWE | |||||||||
| rs208679 | 5’flanking | -6411 | A/G | 0.22 | AA 171 | AG 112 | GG 20 | 0.25 | 0.77 | AA 114 | AG 67 | GG 10 | 0.23 | 0.97 |
| rs10836233 | 5’flanking | -2900 | G/A | 0.30 | GG 155 | GA 111 | AA 36 | 0.30 | 0.02 | GG 106 | GA 60 | AA 24 | 0.28 | 0.002 |
| rs2300182 | Intron1 | 7376 | T/A | 0.23 | TT 203 | TA 87 | AA 13 | 0.19 | 0.35 | TT 128 | TA 57 | AA 6 | 0.18 | 0.91 |
| rs769217 | exon9 (synon) | 22436 | T/C | 0.49 | TT 61 | TC 160 | CC 82 | 0.47 | 0.29 | TT 47 | TC 83 | CC 61 | 0.46 | 0.08 |
| rs7104301 | 3’flanking | 33166 | A/G | 0.23 | AA 173 | AG 115 | GG 15 | 0.24 | 0.46 | AA 106 | AG 69 | GG 16 | 0.26 | 0.32 |
| rs7949972 | 3’flanking | 41570 | C/T | 0.45 | CC 104 | CT 140 | TT 59 | 0.43 | 0.34 | CC 65 | CT 82 | TT 44 | 0.45 | 0.07 |
MAF indicates minor allele frequency; HWE indicates Hardy-Weinberg Equilibrium.