Table 7.
Analyses of association of CAT gene haplotypes with the risk of NIHL between workers with NIHL (+) and without NIHL (-) in the middle noise level exposure group (85~92 dB)
| Loci | Genotype* | Frequency | Chi2 | Pearson’s p | Odds Ratio (95% CI) | |
|---|---|---|---|---|---|---|
|
| ||||||
| NIHL (+) | NIHL (-) | |||||
| ht1 | A A T T A C | 68.00 (0.27) | 168.99 (0.28) | 0.06 | 0.80 | 0.96 (0.69~1.3) |
| ht2 | A G A T A T | 37.99 (0.15) | 105.03 (0.17) | 0.64 | 0.43 | 0.85 (0.57~1.27) |
| ht3 | A G T C A C | 11.00 (0.04) | 11.98 (0.02) | 3.92 | 0.048 | 2.27 (0.99~5.22) |
| ht4 | A G T C G T | 64.01 (0.26) | 144.92 (0.24) | 0.23 | 0.63 | 1.09 (0.77~1.53) |
| ht5 | G G T C A C | 60.00 (0.24) | 149.98 (0.25) | 0.08 | 0.78 | 0.95 (0.67~1.35) |
*
Note: Haplotypes were ignored if the haplotype frequency was less than 3%.