Table 2.
Univariate and multivariable analysis of prognostic factors for 5-year survival in colorectal cancer
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| HR | P > |z| | 95% CI | HR | P > |z| | 95% CI | |||
| KIAA1199 expression High vs. low and none | 7.372 | < 0.001* | 3.522 | 15.432 | 6.509 | < 0.001* | 2.750 | 15.407 |
| Age (years) ≤ 60 vs. > 60 | 1.056 | 0.833 | 0.636 | 1.752 | ||||
| Gender Male vs. Female | 1.347 | 0.255 | 0.807 | 2.251 | ||||
| Location Colon vs. Rectum | 1.349 | 0.241 | 0.818 | 2.226 | ||||
| Differentiation Well and middle vs. poor | 2.041 | 0.009* | 1.191 | 3.497 | 1.743 | 0.121 | 0.864 | 3.517 |
| TNM stage 0 and I vs. II vs. III and IV | 2.349 | < 0.001* | 1.703 | 3.495 | 1.425 | 0.385 | 0.641 | 3.169 |
| T Tis vs. T1 vs. T2 and T3 vs. T4 | 7.141 | < 0.001* | 2.600 | 19.611 | 2.401 | 0.163 | 0.702 | 8.213 |
| N N0 vs. N1 vs. N2 vs. N3 | 1.538 | < 0.001* | 1.251 | 1.891 | 1.107 | 0.634 | 0.728 | 1.683 |
| Preoperative CEA, ng/ml ≤ 5 vs. > 5 | 2.605 | 0.002* | 1.402 | 4.840 | 2.699 | 0.005* | 1.351 | 5.390 |
*
P < 0.05.