Table 2.
Association between FOXO3a expression in tumor tissues and clinicopathological variables of the studied gastric cancer patients
| Variables | FOXO3a expression in tumor tissues | P | ||
|---|---|---|---|---|
|
| ||||
| Low (n=176) | Moderate (n=65) | High (n=48) | ||
| Age (years) | > 0.05 | |||
| < 65 | 113 | 39 | 22 | |
| ≥ 65 | 63 | 26 | 26 | |
| Sex | > 0.05 | |||
| Male | 121 | 47 | 35 | |
| Female | 55 | 18 | 13 | |
| Primary tumor | > 0.05 | |||
| Noncardia | 151 | 55 | 42 | |
| Cardia | 24 | 10 | 6 | |
| Histologic subtype | > 0.05 | |||
| Intestinal | 112 | 41 | 36 | |
| Nonintestinal | 64 | 24 | 12 | |
| Grading | > 0.05 | |||
| Well | 11 | 4 | 2 | |
| Moderate | 30 | 12 | 13 | |
| Poor | 134 | 49 | 33 | |
| Tumor invasion | < 0.05 | |||
| T1/2 | 10 | 4 | 10 | |
| T3 | 71 | 22 | 17 | |
| T4 | 95 | 39 | 21 | |
| Lymph nodes | > 0.05 | |||
| pN0 | 28 | 12 | 9 | |
| pN1 | 33 | 10 | 15 | |
| pN2 | 36 | 17 | 11 | |
| pN3 | 79 | 26 | 13 | |
| stage | >0.05 | |||
| IIA | 20 | 9 | 10 | |
| IIB | 28 | 9 | 14 | |
| IIIA | 36 | 14 | 7 | |
| IIIB | 42 | 12 | 9 | |
| IIIC | 50 | 21 | 8 | |
| Lymph vascular invasion | > 0.05 | |||
| Absence | 121 | 40 | 33 | |
| Presence | 55 | 25 | 15 | |