Table 3.
Tumor necrosis factor-α (TNF-α), superoxide dismutase activity (SOD) and malondialdehyde (MDA) at different time points
| Monitoring Index | Groups (n = 50) | Baseline | OLV 30 | OLV 60 | OLV 90 |
|---|---|---|---|---|---|
| TNF-α (ng/L) | Dexmedetomidine (n = 25) | 16 ± 4 | 20 ± 6 | 24 ± 5*,# | 26 ± 7*,# |
| Control (n = 25) | 14 ± 5 | 18 ± 3 | 34 ± 7* | 38 ± 4* | |
| MDA (nmol/mL) | Dexmedetomidine (n = 25) | 4.85 ± 0.19 | 4.92 ± 0.20 | 5.80 ± 0.45*,# | 7.01 ± 0.38*,# |
| Control (n = 25) | 4.17 ± 0.17 | 4.89 ± 0.18 | 6.75 ± 1.10* | 8.11 ± 1.20* | |
| SOD (U/mL) | Dexmedetomidine (n = 25) | 465 ± 35 | 444 ± 47 | 421 ± 34*,# | 409 ± 36*,# |
| Control (n = 25) | 453 ± 42 | 438 ± 55 | 366 ± 54* | 312 ± 33* |
*
Compared with Baseline, P < 0.05.
#
Compared with Control group, P < 0.05.
Data at the same time point were analyzed by t test for between-group comparisons. Data at different time points were analyzed by one-way analysis of variance (ANOVA) for intro-group comparisons.