Table 4.
Association between genotypes of TP53 genes and OS patients’ survival
| Genotypes | Genotypes | Cases, n | Deaths, n | MST | HR (95% CI)† |
|---|---|---|---|---|---|
| rs12951053 | AA | 54 | 22 | 22.4 | 1.00 |
| AC | 103 | 52 | 19.7 | 1.44 (0.87-2.40) | |
| CC | 53 | 25 | 21.8 | 1.24 (0.69-2.23) | |
| rs1042522 | CC | 59 | 14 | 28.0 | 1.00 |
| CG | 106 | 51 | 21.8 | 1.61 (0.88-2.94) | |
| GG | 44 | 34 | 19.4 | 1.94 (1.03-3.65) | |
| rs8064946 | GG | 68 | 23 | 22.5 | 1.00 |
| GC | 100 | 54 | 19.8 | 1.24 (0.76-2.03) | |
| CC | 41 | 22 | 22.1 | 1.07 (0.59-1.95) | |
| rs9895829 | AA | 173 | 81 | 21.8 | 1.00 |
| AG | 36 | 18 | 19.4 | 1.39 (0.82-2.35) | |
| GG | - | - | - | - | |
| rs12602273 | CC | 89 | 34 | 23.4 | 1.00 |
| CG | 93 | 49 | 19.3 | 1.40 (0.89-2.22) | |
| GG | 27 | 16 | 21.6 | 1.06 (0.58-1.92) |
MST: median survival time.
†
Adjusted for age.