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. 2015 May 14;8:51. doi: 10.1186/s13045-015-0149-x

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© Cheng et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Pattern of IgG and IgM antibody titers following APC8015 treatment. Initial APC8015-2 (investigational form of sipuleucel-T produced using 2 μg/mL of PA2024) in December 2010 and with commercial sipuleucel-T (10 μg/mL PA2024) in December 2012. Rechallenge with commercial sipuleucel-T led to more robust IgG and IgM antibody titers. PAP prostatic acid phosphatase, PA2024 fusion protein comprised of prostatic acid phosphatase and granulocyte-macrophage colony-stimulating factor