Table 1.

In vitro antibiotic susceptibility of planktonic and biofilm S. pseudintermedius strain DSM 25713 cells. MIC, Minimum Inhibitory Concentration; MBC, Minimum Bactericidal Concentration; MBEC₅₀ and MBEC₉₀, Minimum Concentrations Eradicating respectively 50 % and 90 % of Biofilm viability, compared to untreated controls (100 % viability). Assays were performed in triplicate and repeated on two different occasions (n = 6). Values are mg/L

Antibiotics	Planktonic cells		Biofilm cells		C max a
	MIC	MBC	MBEC50	MBEC90
Chloramphenicol	32	256	128	4,096	16.9 [49]
Gentamicin	0.5	0.5	32	32	5-12 [50]
Cefoxitin	16	32	16	1,024	20 [51]
Linezolid	4	32	4	1,024	21.2 [52]
Rifampicin	0.03	0.5	0.03	0.06	10 [53]
Tigecycline	0.5	8	0.5	64	0.25-2.8 [54]
Tetracycline	0.5	8	0.5	64	2 [55]
Vancomycin	2	2	16	32	25 [56]

^aMaximum concentration of drug in serum; references are shown in parentheses