Table 1.

The top six AD risk genes that interact with tau.

Order	Gene	Location (GRCh38.p2 assembly)	Polymorphism	References
1	ApoE	chr19:44905754-44909393	ApoE 2,3,4	Strittmatter et al., 1994; Grupe et al., 2007
2	BIN1	chr2:127048027-127107355	rs 744373	Schellenberg and Montine, 2012
3	CLU	chr:8: 27596917-27615031	rs 11136000	Lambert et al., 2009; Harold et al., 2009
4	ABCA7	chr19:1040101-1065572	rs 3764650	Hollingworth et al., 2011
5	CR1	chr1:207496147-207640647	rs 3818361	Lambert et al., 2009
6	PICALM	chr11:85957684-86069882	rs 3851179	Harold et al., 2009