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Three-dimensional microcomputed tomography (microCT) analysis. Mice were intravenously injected with Raji-luc cells and exposed to different treatments as in Fig. 4. Imaging was performed on day 70 and focused on the lumbar spine and hind limbs. Bone destruction, as a result of lymphoma metastasis, is indicated by the red arrow. Bioluminescence images (day 35) of the same mice are shown in the bottom right corner for comparison.
