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. 2015 Apr 27;5(8):863–881. doi: 10.7150/thno.11852

Figure 8.

Figure 8

DC-mvB16/LLC vaccine induced strong lymphocytotoxicity against both B16 and LLC tumor. (a) Schematic diagram of methods used to generate DC-mvB16/LLC dual vaccine and assess anti-tumor effect. Tumor sizes of (b) B16 or (c) LLC at day 30 after tumor cell challenge. Mice were vaccinated twice at week intervals. Mice were then injected with tumor cells 7 days after the last vaccination. Tumor volume was determined at the end of the study (day 30). Significant difference vs. saline group (**p<0.05). Significant difference vs. DC-mvblank group (++p<0.05). Significant difference vs. DC-mvB16 group (##p<0.05). Reproduced with permission114. Copyright 2014, Elsevier.