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Targeting peptide expressed with Lamp2b was expressed on the external surface of exosomes. (a) Schematic representation of production, harvest and re-administration of targeted self-exosomes for gene delivery. (b) Size distribution of RVG exosomes as measured by NTA peaking at 88 nm diameter. (c) Electron micrograph of phosphotungstic acid stained RVG exosomes. Reproduced with permission134. Copyright 2014, Nature.
