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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Am J Psychiatry. 2014 Dec 12;172(4):353–362. doi: 10.1176/appi.ajp.2014.14020263

Figure 1. CRP genotype (rs1130864) is associated with CRP levels, PTSD diagnosis, and hypervigilance symptoms.

Figure 1

(A) Mean ± SD serum CRP levels in traumatized individuals of each rs1130864 genotype. Individuals with the ‘CC’ genotype have lower serum CRP compared to carriers of the ‘T’ allele (n=137, t=2.73, p=0.007). (B) Number of individuals categorized by PTSD diagnosis (Yes vs. No) in traumatized subjects of each rs1130864 genotype (dominant model, n=2547, t=2.893, p=0.004). (C) Bonferroni-corrected results showing the association between rs1130864 and the 17 different symptom questions on the PSS, covarying for the top 10 principal components. The most robust effect was with the hypervigilance symptom of being overly alert (n=2698, t=4.33, p=1.52×10−05).