Table 2.
Metabolic genes upregulated in iMS- Bmal1 −/−
| Gene symbol | Gene function | ΔExpression (Tam/Veh) | Student’s t test |
|---|---|---|---|
| Agpat3 | Lipogenesis | 1.59 | *** |
| Acadm | Lipolysis | 1.31 | *** |
| Acot7 | Lipolysis | 1.18 | *** |
| Acot9 | Lipolysis | 1.44 | ** |
| Acsl1 | Lipolysis | 1.24 | ** |
| Cd36 | Lipid transport | 1.18 | ** |
| Cox5a | Electron transport chain | 1.24 | *** |
| Cox6a1 | Electron transport chain | 1.30 | * |
| Cpt2 | Lipolysis | 1.11 | * |
| Fabp1 | Lipid transport | 1.28 | * |
| Fabp5 | Lipid transport | 1.29 | ** |
| Fads2 | Lipogenesis | 1.29 | * |
| Ldhb | Lactate metabolism | 1.33 | *** |
| Ndufa8 | Electron transport chain | 1.24 | *** |
| Ndufb8 | Electron transport chain | 1.18 | ** |
| Plin5 | Lipogenesis | 1.41 | *** |
| Sdhc | Electron transport chain | 1.18 | *** |
| Sdhd | Electron transport chain | 1.21 | ** |
| Uqcr10 | Electron transport chain | 1.14 | ** |
Average gene expression changes of metabolic genes that are significantly upregulated in iMS-Bmal1 −/− skeletal muscle. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.