Table 1.
Prevalence of malaria detected by RDT and LAMP
RDT | LAMP | |
---|---|---|
Overall prevalence (%; CI 95 %a) | 0.5; 0.1-0.8 | 1.6; 1.1-2.2 |
19/3983 | 65/3983 | |
Relative proportion positive in: | ||
Only Panb (%; CI 95 %) | 5.3; 0.0-16.4 | 35.4; 23.4-47.4 |
1/19 | 23/65 | |
Pan + P. falciparum c (%; CI 95 %) | 31.6; 8.5-54.6 | 64.6; 52.6-76.6 |
6/19 | 42/65 | |
Only P. falciparum d (%; CI 95 %) | 63.2; 39.2-87.1 | NDe |
12/19 |
Both RDT brands used for malaria screening are two-band RDTs detecting P. falciparum HRP2 and Pan-Plasmodium LDH simultaneously, although with different detection limits (50–100 parasites/μL for P. falciparum HRP2 and 200–500 parasites/μL for Pan-Plasmodium LDH). In contrast, only the Pan-LAMP positive samples were assessed for P. falciparum during the LAMP screening, with a detection limit of 2–5 parasites/μL for both Pan-Plasmodium and P. falciparum
aConfidence intervals for prevalences were calculated using the survey [svy] command in Stata, accounting for household and village sampling/stratification
bPositive for Plasmodium genus only
cPositive for Plasmodium and P. falciparum
dPositive for P. falciparum only
eND = not determined