Table 2.

pIC50 and maximum percentage of stimulation of proteasome inhibitors in different assays

Proteasome inhibitor	pIC50 reported whole cell	pIC50 AlphaLISA (n = 4)	Maximum% stimulation AlphaLISA	pIC50 DELFIA (n = 4)	Maximum% stimulation DELFIA
Epoxomicin	8.17	7.64 ± 0.09	178 ± 47	7.74 ± 0.24	177 ± 15
Bortezomib	7.05	7.95 ± 0.08	178 ± 24	8.16 ± 0.05	180 ± 14
Gliotoxin	5.66	5.88 ± 0.73	217 ± 53	6.12 ± 0.27	180 ± 26
MG132	7.65	7.17 ± 0.04	236 ± 36	7.41 ± 0.21	189 ± 55
MG115	7.01	6.88 ± 0.09	208 ± 22	6.92 ± 0.21	185 ± 17
Lactacystin	5.83	5.81 ± 0.07	217 ± 27	6.06 ± 0.22	193 ± 32
Clasto-lactacystin β lactone	5.83	6.30 ± 0.09	195 ± 19	6.48 ± 0.18	198 ± 17