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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: J R Stat Soc Ser C Appl Stat. 2014 Oct 14;64(3):433–449. doi: 10.1111/rssc.12081

Table 5.

Simulations comparing MLEs under internal validation design for logistic-mixed regression with general outcome misclassification and two covariates (J=4)

Model β^1 β^2 σu^2 σu^2 ψ
Mean
(SD)
95%
Coverage
Mean
(SD)
95%
Coverage
Mean
(SD)
Mean
(SD)
Mean
(SD)
Naive 0.90 (0.10) 82.8% 0.21 (0.03) 0 1.15 (0.15)
Ideal 1.00 (0.11) 92.6% 0.50 (0.03) 96.6% 1.00 (0.14)
General Misclassification†† 0.99 (0.20) 93.6% 0.50 (0.05) 94.4% 1.00 (0.30) 1.01 (0.23) 0.52 (0.16)
Independent CorrelatedDifferential Misclassification††† 1.00 (0.20) 95.8% 0.49 (0.05) 93.6% 1.11 (0.31) 1.38 (0.26)
Uncorrelated Differential Misclassification†††† 1.07 (0.22) 90.2% 0.49 (0.05) 89.6% 2.41 (0.22)
Nondifferential Misclassification††††† 1.53 (0.19) 16.4% 0.48 (0.05) 89.8% 2.39 (0.22)
Selected Model 1.00 (0.20) 93.2% 0.50 (0.05) 93.2% 1.02 (0.36) 1.02 (0.23) 0.54 (0.16)

ML based on (11) and (12); 500 simulations under each set of conditions with (β0, β1, β2, σ2u, σ2u*, ψ)= (0, 1, 0.5, 1, 1, 0.5), (γ0, γ1, γ2, γ3, γ4, γ5)= (−3, 0.05, 0.2, 0.4, 1.5, 3). X1 ~Bernoulli(0.5) and X2 ~ N(0,4). nm=800, nv=200.

††

Converged 499 times.

†††

Converged 500 times.

††††

Converged 468 times.

†††††

Converged 476 times.